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Welcome to the doTERRA Serenity Sleep System!


Sleep is essential for the health of our brain and body. It helps us to restore and rejuvenate, grow muscle, repair tissue, and synthesize hormones. However, many of us struggle to get the quality sleep we need. That's where the doTERRA Serenity Sleep System comes in. This revolutionary product includes three amazing products: the Serenity Essential Oil Blend, the Serenity Sleep Stick, and the Serenity Soft Gels. Clinically tested and proven to improve sleep quality, reduce inflammation, and even reverse biological age in various epigenetic clocks, the doTERRA Serenity Sleep System is the solution you've been looking for.

doTERRA Serenity Sleep System - Click to purchase

How it Works


The Serenity Sleep System works by supporting healthy sleep and circadian rhythms. It improves sleep, glucose metabolism, and cellular fitness, and regulates sleep, immunity, and inflammatory response. The system includes three products that work together to provide the best results:

  • Serenity Essential Oil Blend: A calming and soothing blend of essential oils that promotes relaxation and restful sleep.

  • Serenity Sleep Stick: A topical stick that provides a convenient and mess-free way to apply the Serenity Essential Oil Blend.

  • Serenity Soft Gels: A dietary supplement that contains a combination of essential oils and natural ingredients that promote restful sleep.

The Benefits


The benefits of the Serenity Sleep System are numerous and backed by clinical research. In a trial, participants reported improvements in their quality of life, such as general health, social activities, peace and calm, and daily functioning. The trial also measured objective markers of inflammation, glucose metabolism, and cellular fitness in the blood, as well as epigenetic patterns of methylation that reflect biological age. The results showed that the Serenity Sleep System reduced inflammation, improved glucose metabolism and cellular fitness, and reversed biological age in various epigenetic clocks.

The Evidence



dōTERRA conducted an extensive trial of the Serenity Sleep System with the results being released in 2023. The trial tested the effects of the Serenity Sleep System, which consists of three products: essential oil blend, sleep stick, and soft gels, on sleep quality and various health outcomes. The trial involved 103 participants who used the products for six weeks and completed surveys and blood tests before and after the intervention. The findings are summarized below and a more detailed video presentation of the results, presented by Dr. Russell Osguthorpe, MD and Nicole Stevens, PhD, can be watched at the bottom of this page:

  • Quality of life and subjective measures: The trial participants reported improvements in their quality of life, such as general health, social activities, peace and calm, and daily functioning, after using the Serenity Sleep System. They also reported reductions in discomfort, nervousness, and sadness. The surveys used validated scales to measure these outcomes.

  • Objective measures and epigenetic data: The trial also measured objective markers of inflammation, glucose metabolism, and cellular fitness in the blood, as well as epigenetic patterns of methylation that reflect biological age. The results showed that the Serenity Sleep System reduced inflammation, as measured by C-reactive protein (CRP), improved glucose metabolism, as measured by hemoglobin A1c (HbA1c), and enhanced cellular fitness, as measured by telomere length. The Serenity Sleep System also reversed biological age in various epigenetic clocks, such as Horvath, Hannum, PhenoAge, GrimAge, OmicAge, and others, which are based on different sets of genes and biomarkers.

  • Regular vs irregular sleepers: The trial also compared the effects of the Serenity Sleep System between regular sleepers (who had consistent sleep patterns) and irregular sleepers (who had chaotic sleep patterns). The results showed that both groups benefited from the Serenity Sleep System, but the regular sleepers had more pronounced benefits in most of the epigenetic clocks and inflammatory markers. The regular sleepers also had lower baseline levels of CRP and higher baseline levels of telomere length, indicating that they had a healthier lifestyle than the irregular sleepers. The trial authors suggested that the Serenity Sleep System works best when combined with a healthy lifestyle that supports regular sleep patterns.

After 6-weeks of use, the Serenity Sleep System effectively reversed biological age markers on average by at least 0.7-years and as much as 4.45-years.

How To Use The Serenity Sleep System

Get Some Quality Sleep

and start turning your clocks back!

Serenity Sleep System Trial Results Presentation Video

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412 E 41st St #4, Garden City, ID 83714

**The statements made have not been evaluated by the Food and Drug Administration. The efficacy of these products has not been confirmed by FDA-approved research. These products are not intended to diagnose, treat, cure or prevent any disease. All information presented here is not meant as a substitute for or alternative to information from health care practitioners. Please consult your health care professional about potential interactions or other possible complications before using any product. The Federal Food, Drug, and Cosmetic Act require this notice.